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The research landscape in homeopathy is slowly shaping up. The planning and execution of large observational studies is difficult in terms of the availability of the number of patients in homeopathy, RCTs validity to homeopathic paradigm has been called into question time and again. In such a scenario, the real-world cases are the best way to lay a strong foundation on which not only research, but clinical guidelines and expertise may also be better informed. Students and practitioners learn better through case studies in homeopathy. With this idea in the background, the scientific team of International Academy of Classical Homeopathy (IACH), Greece, has focused on the building of solid evidence through case reports and series. Prof George Vithoulkas heads this team and under his supervision, these studies have brought forth evidence not just about the clinical effect of classical homeopathy, but also about the concepts of health and disease. Through this presentation, one may see that the role of case reports is not as small as previously believed and that there are many lessons to learn from them for future research and clinical practice.